Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate. [electronic resource]
- Chemical research in toxicology
- 390-400 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
0893-228X
10.1021/tx00039a017 doi
Acetylcysteine--chemistry Animals Biotransformation Cell-Free System Chromatography, High Pressure Liquid Glutathione--metabolism In Vitro Techniques Inactivation, Metabolic Magnetic Resonance Spectroscopy Male Mercaptoethanol--chemistry Microsomes, Liver--metabolism Mitomycin--chemistry NADP--metabolism Oxidation-Reduction Rats Rats, Sprague-Dawley Spectrophotometry, Ultraviolet Sulfhydryl Compounds--metabolism