Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice. [electronic resource]
- Proceedings of the National Academy of Sciences of the United States of America Oct 1994
- 10460-4 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0027-8424
10.1073/pnas.91.22.10460 doi
Adsorption Animals Base Sequence Breast Cell Division--drug effects Cell Transformation, Neoplastic--drug effects Cyanoacrylates Exons Female Genes, ras Humans Male Mice Mice, Nude Molecular Sequence Data Mutagenesis, Site-Directed Oligonucleotides, Antisense--pharmacokinetics Point Mutation Polymerase Chain Reaction Proto-Oncogene Proteins p21(ras)--biosynthesis RNA, Messenger--biosynthesis Urinary Bladder Neoplasms--genetics