TY  - GEN
AU  - Minarini,A
AU  - Bolognesi,M L
AU  - Budriesi,R
AU  - Canossa,M
AU  - Chiarini,A
AU  - Spampinato,S
AU  - Melchiorre,C
TI  - Design, synthesis, and biological activity of methoctramine-related tetraamines bearing an 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4] benzodiazepin-6-one moiety: structural requirements for optimum occupancy of muscarinic receptor subtypes as revealed by symmetrical and unsymmetrical polyamines
SN  - 0022-2623
PY  - 1994///1103
KW  - Animals
KW  - Atrial Function
KW  - Benzodiazepines
KW  - chemical synthesis
KW  - Cells, Cultured
KW  - Cerebral Cortex
KW  - metabolism
KW  - Drug Design
KW  - Female
KW  - Guinea Pigs
KW  - Heart Atria
KW  - drug effects
KW  - Ileum
KW  - Male
KW  - Molecular Structure
KW  - Muscarinic Antagonists
KW  - Muscle Contraction
KW  - Myocardial Contraction
KW  - Myocardium
KW  - Polyamines
KW  - Rats
KW  - Receptors, Muscarinic
KW  - Structure-Activity Relationship
KW  - Submandibular Gland
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm00046a021
ER  -