Minarini, A <br/><br/>
Design, synthesis, and biological activity of methoctramine-related tetraamines bearing an 11-acetyl-5,11-dihydro-6H-pyrido[2,3-b][1,4] benzodiazepin-6-one moiety: structural requirements for optimum occupancy of muscarinic receptor subtypes as revealed by symmetrical and unsymmetrical polyamines.  [electronic resource] 

 -  Journal of medicinal chemistry  Sep 1994 
 - 3363-72 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm00046a021  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Atrial Function<br/>Benzodiazepines--chemical synthesis<br/>Cells, Cultured<br/>Cerebral Cortex--metabolism<br/>Drug Design<br/>Female<br/>Guinea Pigs<br/>Heart Atria--drug effects<br/>Ileum--drug effects<br/>Male<br/>Molecular Structure<br/>Muscarinic Antagonists<br/>Muscle Contraction--drug effects<br/>Myocardial Contraction--drug effects<br/>Myocardium--metabolism<br/>Polyamines--chemical synthesis<br/>Rats<br/>Receptors, Muscarinic--metabolism<br/>Structure-Activity Relationship<br/>Submandibular Gland--metabolism