TY  - GEN
AU  - Schinkel,A H
AU  - Smit,J J
AU  - van Tellingen,O
AU  - Beijnen,J H
AU  - Wagenaar,E
AU  - van Deemter,L
AU  - Mol,C A
AU  - van der Valk,M A
AU  - Robanus-Maandag,E C
AU  - te Riele,H P
TI  - Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
SN  - 0092-8674
PY  - 1994///0623
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 1
KW  - Animals
KW  - Blood-Brain Barrier
KW  - drug effects
KW  - Capillaries
KW  - chemistry
KW  - Carrier Proteins
KW  - analysis
KW  - Drug Resistance
KW  - genetics
KW  - Epithelial Cells
KW  - Female
KW  - Intestine, Small
KW  - Ivermectin
KW  - blood
KW  - Male
KW  - Membrane Glycoproteins
KW  - Mice
KW  - Mice, Knockout
KW  - Mutagenesis, Insertional
KW  - RNA, Messenger
KW  - Tissue Distribution
KW  - Vinblastine
KW  - pharmacokinetics
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/0092-8674(94)90212-7
ER  -