TY  - GEN
AU  - Hiroya,K
AU  - Murakami,Y
AU  - Shimizu,T
AU  - Hatano,M
AU  - Ortiz de Montellano,P R
TI  - Differential roles of Glu318 and Thr319 in cytochrome P450 1A2 catalysis supported by NADPH-cytochrome P450 reductase and tert-butyl hydroperoxide
SN  - 0003-9861
PY  - 1994///0608
KW  - Amino Acid Sequence
KW  - Animals
KW  - Binding Sites
KW  - Catalysis
KW  - Cytochrome P-450 CYP1A2
KW  - Cytochrome P-450 Enzyme System
KW  - biosynthesis
KW  - Glutamates
KW  - Glutamic Acid
KW  - Kinetics
KW  - Microsomes, Liver
KW  - enzymology
KW  - Mutagenesis, Site-Directed
KW  - NADPH-Ferrihemoprotein Reductase
KW  - isolation & purification
KW  - Oxidoreductases
KW  - Peroxides
KW  - metabolism
KW  - Rats
KW  - Recombinant Proteins
KW  - Saccharomyces cerevisiae
KW  - Threonine
KW  - tert-Butylhydroperoxide
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1006/abbi.1994.1184
ER  -