TY - GEN AU - Takeuchi,K AU - Happ,A M AU - Mais,D E AU - Layman,N AU - Utterback,B G AU - Wyss,V L AU - Jakubowski,J A TI - Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition--I. Synthesis, structure-activity relationship, and evaluation of substituted omega-phenyl-omega-(3-pyridyl)alkenoic acids SN - 0968-0896 PY - 1995///0421 KW - 6-Ketoprostaglandin F1 alpha KW - blood KW - Alkenes KW - chemical synthesis KW - Animals KW - Drug Evaluation, Preclinical KW - Humans KW - In Vitro Techniques KW - Molecular Structure KW - Rats KW - Rats, Sprague-Dawley KW - Receptors, Thromboxane KW - antagonists & inhibitors KW - Structure-Activity Relationship KW - Thromboxane B2 KW - Thromboxane-A Synthase N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/s0968-0896(00)82174-4 ER -