Joseph, D B

The kappa opioid receptor expressed on the mouse R1.1 thymoma cell line down-regulates without desensitizing during chronic opioid exposure. [electronic resource] - The Journal of pharmacology and experimental therapeutics Mar 1995 - 970-6 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-3565


3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer
Adenylate Cyclase Toxin
Adenylyl Cyclases--metabolism
Animals
Benzeneacetamides
Cell Membrane--metabolism
Down-Regulation
In Vitro Techniques
Mice
Naloxone--metabolism
Naltrexone--analogs & derivatives
Pertussis Toxin
Pyrrolidines--administration & dosage
Receptors, Opioid, kappa--agonists
Thymoma
Tumor Cells, Cultured
Virulence Factors, Bordetella--pharmacology