TY  - GEN
AU  - Hancock,A A
AU  - Buckner,S A
AU  - Giardina,W J
AU  - Brune,M E
AU  - Lee,J Y
AU  - Morse,P A
AU  - Oheim,K W
AU  - Stanisic,D S
AU  - Warner,R B
AU  - Kerkman,D J
TI  - Preclinical pharmacological actions of (+/-)-(1'R*,3R*)-3-phenyl-1- [1',2',3',4'-tetrahydro-5',6'-methylene-dioxy-1'-naphthalenyl) methyl] pyrrolidine methanesulfonate (ABT-200), a potential antidepressant agent that antagonizes alpha-2 adrenergic receptors and inhibits the neuronal uptake of norepinephrine
SN  - 0022-3565
PY  - 1995///0414
KW  - Adrenergic Uptake Inhibitors
KW  - pharmacology
KW  - Adrenergic alpha-2 Receptor Antagonists
KW  - Animals
KW  - Antidepressive Agents
KW  - Behavior, Animal
KW  - drug effects
KW  - Blood Pressure
KW  - Clonidine
KW  - Guinea Pigs
KW  - Heart Rate
KW  - Hippocampus
KW  - metabolism
KW  - In Vitro Techniques
KW  - Male
KW  - Motor Activity
KW  - Mydriasis
KW  - chemically induced
KW  - Neurons
KW  - Olfactory Bulb
KW  - physiology
KW  - Pyrrolidines
KW  - Rabbits
KW  - Radioligand Assay
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Synaptosomes
KW  - Tyramine
KW  - analogs & derivatives
N1  - Publication Type: Journal Article
ER  -