Arnér, E S <br/><br/>
1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity.  [electronic resource] 

 -  The Journal of biological chemistry  Feb 1995 
 - 3479-82 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.270.8.3479  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cattle<br/>Dinitrochlorobenzene--pharmacology<br/>Enzyme Induction<br/>Glutathione--metabolism<br/>Humans<br/>Kinetics<br/>NADH, NADPH Oxidoreductases--biosynthesis<br/>NADPH Oxidases<br/>Thioredoxin-Disulfide Reductase--antagonists & inhibitors