Are we doing too many animal biodisposition investigations before phase I studies in man? A re-evaluation of the timing and extent of ADME studies. [electronic resource]
- European journal of drug metabolism and pharmacokinetics
- 283-93 p. digital
Publication Type: Journal Article
0378-7966
10.1007/BF03188932 doi
Animals Clinical Trials, Phase I as Topic Cytochrome P-450 Enzyme System--physiology Humans Pharmacokinetics Protein Binding Time Factors