Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase (PEPCK) gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of PEPCK gene expression. [electronic resource]
- The Journal of biological chemistry Jun 1995
- 15501-6 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.270.26.15501 doi
Amino Acid Sequence Androstadienes--pharmacology Base Sequence Gene Expression Regulation, Enzymologic--drug effects Insulin--pharmacology Molecular Sequence Data Phosphatidylinositol 3-Kinases Phosphoenolpyruvate Carboxykinase (GTP)--genetics Phosphotransferases (Alcohol Group Acceptor)--physiology Protein Kinase C--physiology Protein Serine-Threonine Kinases--physiology Ribosomal Protein S6 Kinases Tetradecanoylphorbol Acetate--pharmacology Tumor Cells, Cultured Wortmannin