TY - GEN AU - Lee,J W AU - DeMets,D L TI - Group sequential comparison of changes: ad-hoc versus more exact method SN - 0006-341X PY - 1995///0630 KW - Analysis of Variance KW - Biometry KW - methods KW - Clinical Trials as Topic KW - Humans KW - Models, Statistical KW - National Institutes of Health (U.S.) KW - United States N1 - Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S ER -