Wiley, R G

Destruction of the cholinergic basal forebrain using immunotoxin to rat NGF receptor: modeling the cholinergic degeneration of Alzheimer's disease. [electronic resource] - Journal of the neurological sciences Feb 1995 - 157-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0022-510X

10.1016/0022-510x(94)00226-e doi


Alzheimer Disease
Animals
Antibodies, Monoclonal--administration & dosage
Avoidance Learning--physiology
Basal Ganglia--drug effects
Behavior, Animal--physiology
Cell Count
Cells, Cultured
Cholinergic Fibers--drug effects
Disease Models, Animal
Ganglia, Sympathetic--cytology
Humans
Immunoconjugates
Immunoglobulin G--immunology
Immunotoxins--administration & dosage
Injections, Intraventricular
Learning Disabilities--chemically induced
Male
Membrane Glycoproteins--drug effects
N-Glycosyl Hydrolases
Neurons--drug effects
Plant Proteins--administration & dosage
Rats
Rats, Sprague-Dawley
Receptor, Nerve Growth Factor
Receptors, Nerve Growth Factor--drug effects
Ribosome Inactivating Proteins, Type 1
Saporins
Septum Pellucidum--drug effects
Substantia Innominata--drug effects