Akalin, E

Blocking cell microtubule assembly inhibits the alloimmune response in vitro and prolongs renal allograft survival by inhibition of Th1 and sparing of Th2 cell function in vivo. [electronic resource] - Journal of the American Society of Nephrology : JASN Jan 1995 - 1418-25 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1046-6673

10.1681/ASN.V571418 doi


Animals
Antibody Formation--drug effects
Colchicine--pharmacology
Cytokines--metabolism
Graft Survival--drug effects
Immune System--drug effects
Isoantigens--immunology
Kidney Transplantation
Lymphocyte Culture Test, Mixed
Male
Microtubules--drug effects
Rats
Rats, Inbred BN
Rats, Inbred Lew
T-Lymphocytes, Cytotoxic--cytology
T-Lymphocytes, Regulatory--drug effects
Th1 Cells--physiology
Th2 Cells--physiology