TY - GEN AU - Furitsu,T AU - Tsujimura,T AU - Tono,T AU - Ikeda,H AU - Kitayama,H AU - Koshimizu,U AU - Sugahara,H AU - Butterfield,J H AU - Ashman,L K AU - Kanayama,Y TI - Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product SN - 0021-9738 PY - 1993///1112 KW - Amino Acid Sequence KW - Animals KW - Base Sequence KW - Cell Line KW - DNA Primers KW - Granulocyte-Macrophage Colony-Stimulating Factor KW - pharmacology KW - Humans KW - Interleukin-3 KW - Leukemia, Mast-Cell KW - genetics KW - Mice KW - Molecular Sequence Data KW - Phosphotyrosine KW - Point Mutation KW - Polymerase Chain Reaction KW - Proto-Oncogene Mas KW - Proto-Oncogene Proteins KW - biosynthesis KW - Proto-Oncogene Proteins c-kit KW - Proto-Oncogenes KW - Receptor Protein-Tyrosine Kinases KW - Receptors, Colony-Stimulating Factor KW - Recombinant Proteins KW - Transfection KW - Tumor Cells, Cultured KW - Tyrosine KW - analogs & derivatives N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI116761 ER -