Furitsu, T

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product. [electronic resource] - The Journal of clinical investigation Oct 1993 - 1736-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9738

10.1172/JCI116761 doi


Amino Acid Sequence
Animals
Base Sequence
Cell Line
DNA Primers
Granulocyte-Macrophage Colony-Stimulating Factor--pharmacology
Humans
Interleukin-3--pharmacology
Leukemia, Mast-Cell--genetics
Mice
Molecular Sequence Data
Phosphotyrosine
Point Mutation
Polymerase Chain Reaction
Proto-Oncogene Mas
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-kit
Proto-Oncogenes
Receptor Protein-Tyrosine Kinases--biosynthesis
Receptors, Colony-Stimulating Factor--biosynthesis
Recombinant Proteins--pharmacology
Transfection
Tumor Cells, Cultured
Tyrosine--analogs & derivatives