TY - GEN AU - Jiang,G AU - McKenzie,T L AU - Conrad,D G AU - Shechter,I TI - Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase SN - 0021-9258 PY - 1993///0713 KW - Amino Acid Sequence KW - Animals KW - Base Sequence KW - Carcinoma, Hepatocellular KW - Cell Division KW - Cloning, Molecular KW - DNA, Neoplasm KW - Farnesyl-Diphosphate Farnesyltransferase KW - biosynthesis KW - Gene Expression Regulation, Enzymologic KW - drug effects KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Hydroxycholesterols KW - pharmacology KW - Hydroxymethylglutaryl CoA Reductases KW - Kinetics KW - Liver KW - enzymology KW - Liver Neoplasms KW - Lovastatin KW - Molecular Sequence Data KW - Oligodeoxyribonucleotides KW - Polymerase Chain Reaction KW - RNA KW - isolation & purification KW - RNA, Messenger KW - metabolism KW - Rats KW - Sequence Homology, Amino Acid KW - Transcription, Genetic KW - Tumor Cells, Cultured N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't ER -