Jiang, G

Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase. [electronic resource] - The Journal of biological chemistry Jun 1993 - 12818-24 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0021-9258


Amino Acid Sequence
Animals
Base Sequence
Carcinoma, Hepatocellular
Cell Division
Cloning, Molecular
DNA, Neoplasm
Farnesyl-Diphosphate Farnesyltransferase--biosynthesis
Gene Expression Regulation, Enzymologic--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Humans
Hydroxycholesterols--pharmacology
Hydroxymethylglutaryl CoA Reductases--biosynthesis
Kinetics
Liver--enzymology
Liver Neoplasms
Lovastatin--pharmacology
Molecular Sequence Data
Oligodeoxyribonucleotides
Polymerase Chain Reaction
RNA--isolation & purification
RNA, Messenger--metabolism
Rats
Sequence Homology, Amino Acid
Transcription, Genetic--drug effects
Tumor Cells, Cultured