TY - GEN AU - Wade,M L AU - Voelkel,N F AU - Fitzpatrick,F A TI - "Suicide" inactivation of prostaglandin I2 synthase: characterization of mechanism-based inactivation with isolated enzyme and endothelial cells SN - 0003-9861 PY - 1995///0918 KW - 6-Ketoprostaglandin F1 alpha KW - metabolism KW - Animals KW - Aorta KW - enzymology KW - Binding, Competitive KW - Cattle KW - Cyclooxygenase Inhibitors KW - pharmacology KW - Cytochrome P-450 Enzyme Inhibitors KW - Cytochrome P-450 Enzyme System KW - isolation & purification KW - Endothelium, Vascular KW - Intramolecular Oxidoreductases KW - Isomerases KW - antagonists & inhibitors KW - Kinetics KW - Microsomes KW - Models, Theoretical KW - Prostaglandin H2 KW - Prostaglandins H N1 - Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1006/abbi.1995.1417 ER -