Wade, M L

"Suicide" inactivation of prostaglandin I2 synthase: characterization of mechanism-based inactivation with isolated enzyme and endothelial cells. [electronic resource] - Archives of biochemistry and biophysics Aug 1995 - 453-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0003-9861

10.1006/abbi.1995.1417 doi


6-Ketoprostaglandin F1 alpha--metabolism
Animals
Aorta--enzymology
Binding, Competitive
Cattle
Cyclooxygenase Inhibitors--pharmacology
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--isolation & purification
Endothelium, Vascular--enzymology
Intramolecular Oxidoreductases
Isomerases--antagonists & inhibitors
Kinetics
Microsomes--enzymology
Models, Theoretical
Prostaglandin H2
Prostaglandins H--metabolism