TY  - GEN
AU  - Spek,C A
AU  - Greengard,J S
AU  - Griffin,J H
AU  - Bertina,R M
AU  - Reitsma,P H
TI  - Two mutations in the promoter region of the human protein C gene both cause type I protein C deficiency by disruption of two HNF-3 binding sites
SN  - 0021-9258
PY  - 1995///1204
KW  - Animals
KW  - Base Sequence
KW  - Binding Sites
KW  - DNA
KW  - genetics
KW  - DNA Primers
KW  - DNA-Binding Proteins
KW  - isolation & purification
KW  - Gene Expression
KW  - HeLa Cells
KW  - Hominidae
KW  - Humans
KW  - Liver Neoplasms
KW  - Liver Neoplasms, Experimental
KW  - Models, Structural
KW  - Molecular Sequence Data
KW  - Molecular Weight
KW  - Nucleic Acid Conformation
KW  - Point Mutation
KW  - Polymerase Chain Reaction
KW  - Promoter Regions, Genetic
KW  - Protein C
KW  - Protein C Deficiency
KW  - Recombinant Proteins
KW  - Transcription Factors
KW  - Transcription, Genetic
KW  - Tumor Cells, Cultured
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.270.41.24216
ER  -