Spek, C A <br/><br/>
Two mutations in the promoter region of the human protein C gene both cause type I protein C deficiency by disruption of two HNF-3 binding sites.  [electronic resource] 

 -  The Journal of biological chemistry  Oct 1995 
 - 24216-21 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.270.41.24216  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Base Sequence<br/>Binding Sites<br/>DNA--genetics<br/>DNA Primers<br/>DNA-Binding Proteins--isolation & purification<br/>Gene Expression<br/>HeLa Cells<br/>Hominidae--genetics<br/>Humans<br/>Liver Neoplasms<br/>Liver Neoplasms, Experimental<br/>Models, Structural<br/>Molecular Sequence Data<br/>Molecular Weight<br/>Nucleic Acid Conformation<br/>Point Mutation<br/>Polymerase Chain Reaction<br/>Promoter Regions, Genetic<br/>Protein C--genetics<br/>Protein C Deficiency<br/>Recombinant Proteins--isolation & purification<br/>Transcription Factors--isolation & purification<br/>Transcription, Genetic<br/>Tumor Cells, Cultured