TY - GEN AU - Low,J E AU - Metz,A L AU - Mertz,T E AU - Henry,S P AU - Knowlton,P AU - Loewen,G AU - Sommers,C S AU - Robertson,D G AU - Olszewski,B J AU - Schroeder,R L TI - Cardiac hypertrophy in rats after intravenous administration of CI-959, a novel antiinflammatory compound: morphologic features and pharmacokinetic and pharmacodynamic mechanisms SN - 0160-2446 PY - 1995///1107 KW - Administration, Oral KW - Adrenergic alpha-Antagonists KW - administration & dosage KW - Adrenergic beta-Antagonists KW - Animals KW - Anti-Inflammatory Agents, Non-Steroidal KW - Blood Pressure KW - drug effects KW - Cardiomegaly KW - chemically induced KW - Catecholamines KW - blood KW - Cells, Cultured KW - Creatine Kinase KW - metabolism KW - Disease Models, Animal KW - Glycogen KW - Heart KW - Heart Rate KW - Infusion Pumps, Implantable KW - Infusions, Intravenous KW - L-Lactate Dehydrogenase KW - Microscopy, Electron KW - Myocardium KW - cytology KW - Rats KW - Rats, Sprague-Dawley KW - Rats, Wistar KW - Tetrazoles KW - Thiophenes N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.1097/00005344-199506000-00011 ER -