TY  - GEN
AU  - Bürgisser,D M
AU  - Thöny,B
AU  - Redweik,U
AU  - Hess,D
AU  - Heizmann,C W
AU  - Huber,R
AU  - Nar,H
TI  - 6-Pyruvoyl tetrahydropterin synthase, an enzyme with a novel type of active site involving both zinc binding and an intersubunit catalytic triad motif; site-directed mutagenesis of the proposed active center, characterization of the metal binding site and modelling of substrate binding
SN  - 0022-2836
PY  - 1995///1122
KW  - Alcohol Oxidoreductases
KW  - chemistry
KW  - Amino Acid Sequence
KW  - Animals
KW  - Apoenzymes
KW  - Base Sequence
KW  - Binding Sites
KW  - DNA Primers
KW  - Escherichia coli
KW  - Humans
KW  - Macromolecular Substances
KW  - Magnesium
KW  - analysis
KW  - Models, Molecular
KW  - Molecular Sequence Data
KW  - Mutagenesis, Site-Directed
KW  - Phosphorus-Oxygen Lyases
KW  - Point Mutation
KW  - Protein Structure, Secondary
KW  - Rats
KW  - Recombinant Fusion Proteins
KW  - biosynthesis
KW  - Recombinant Proteins
KW  - Salmon
KW  - Sequence Homology, Amino Acid
KW  - Spectrophotometry, Atomic
KW  - Zinc
KW  - metabolism
N1  - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1006/jmbi.1995.0558
ER  -