Van Calenbergh, S

Synthesis and structure-activity relationships of analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine, a selective inhibitor of trypanosomal glycosomal glyceraldehyde-3-phosphate dehydrogenase. [electronic resource] - Journal of medicinal chemistry Sep 1995 - 3838-49 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-2623

10.1021/jm00019a014 doi


Animals
Binding Sites
Crystallography, X-Ray
Deoxyadenosines--chemical synthesis
Enzyme Inhibitors--chemical synthesis
Glyceraldehyde-3-Phosphate Dehydrogenases--antagonists & inhibitors
Humans
Magnetic Resonance Spectroscopy
Molecular Conformation
Protein Binding
Structure-Activity Relationship
Trypanosoma brucei brucei--enzymology