TY  - GEN
AU  - Siegel,S A
AU  - Shealy,D J
AU  - Nakada,M T
AU  - Le,J
AU  - Woulfe,D S
AU  - Probert,L
AU  - Kollias,G
AU  - Ghrayeb,J
AU  - Vilcek,J
AU  - Daddona,P E
TI  - The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo
SN  - 1043-4666
PY  - 1995///0621
KW  - Animals
KW  - Antibodies, Monoclonal
KW  - immunology
KW  - Blood Coagulation Factors
KW  - biosynthesis
KW  - Cachexia
KW  - physiopathology
KW  - Cell Adhesion
KW  - drug effects
KW  - Cell Adhesion Molecules
KW  - Cell Division
KW  - Cells, Cultured
KW  - E-Selectin
KW  - Endothelium, Vascular
KW  - Fibroblasts
KW  - Gene Expression Regulation
KW  - Humans
KW  - Infliximab
KW  - Intercellular Adhesion Molecule-1
KW  - Interleukin-6
KW  - metabolism
KW  - Mice
KW  - Mice, Transgenic
KW  - Neutralization Tests
KW  - Neutrophils
KW  - Recombinant Fusion Proteins
KW  - Recombinant Proteins
KW  - pharmacology
KW  - Respiratory Burst
KW  - Thromboplastin
KW  - Tumor Necrosis Factor-alpha
KW  - antagonists & inhibitors
KW  - Umbilical Veins
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1006/cyto.1995.1003
ER  -