Siegel, S A <br/><br/>
The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo.  [electronic resource] 

 -  Cytokine  Jan 1995 
 - 15-25 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1043-4666 
<br/><br/><label>Standard No.: </label>10.1006/cyto.1995.1003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--immunology<br/>Blood Coagulation Factors--biosynthesis<br/>Cachexia--physiopathology<br/>Cell Adhesion--drug effects<br/>Cell Adhesion Molecules--biosynthesis<br/>Cell Division--drug effects<br/>Cells, Cultured<br/>E-Selectin<br/>Endothelium, Vascular--drug effects<br/>Fibroblasts--drug effects<br/>Gene Expression Regulation--drug effects<br/>Humans<br/>Infliximab<br/>Intercellular Adhesion Molecule-1--biosynthesis<br/>Interleukin-6--metabolism<br/>Mice<br/>Mice, Transgenic<br/>Neutralization Tests<br/>Neutrophils--drug effects<br/>Recombinant Fusion Proteins--immunology<br/>Recombinant Proteins--pharmacology<br/>Respiratory Burst--drug effects<br/>Thromboplastin<br/>Tumor Necrosis Factor-alpha--antagonists & inhibitors<br/>Umbilical Veins