TY - GEN AU - Carson,M R AU - Travis,S M AU - Welsh,M J TI - The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity SN - 0021-9258 PY - 1995///0222 KW - 3T3 Cells KW - Adenosine Triphosphate KW - analogs & derivatives KW - Adenylyl Imidodiphosphate KW - pharmacology KW - Amino Acid Sequence KW - Animals KW - Azides KW - metabolism KW - Binding Sites KW - Chloride Channels KW - chemistry KW - Conserved Sequence KW - Cyclic AMP-Dependent Protein Kinases KW - Cystic Fibrosis Transmembrane Conductance Regulator KW - Genetic Variation KW - HeLa Cells KW - Humans KW - Ion Channel Gating KW - Lysine KW - Membrane Potentials KW - Membrane Proteins KW - Mice KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - Patch-Clamp Techniques KW - Phosphorylation KW - Point Mutation KW - Recombinant Proteins KW - Transfection N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.270.4.1711 ER -