TY - GEN AU - Zembowicz,A AU - Hatchett,R J AU - Radziszewski,W AU - Gryglewski,R J TI - Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase SN - 0022-3565 PY - 1994///0127 KW - Amino Acid Oxidoreductases KW - antagonists & inhibitors KW - Animals KW - Aorta, Thoracic KW - drug effects KW - Azoles KW - Benzamides KW - pharmacology KW - Cattle KW - Drug Interactions KW - Endothelium, Vascular KW - Enzyme Activation KW - Female KW - Glutathione Peroxidase KW - metabolism KW - In Vitro Techniques KW - Isoindoles KW - Male KW - Muscle Relaxation KW - Muscle, Smooth, Vascular KW - Nitric Oxide Synthase KW - Organoselenium Compounds KW - Rabbits KW - Rats KW - Rats, Wistar KW - Sulfhydryl Compounds KW - Swine N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't ER -