Zembowicz, A <br/><br/>
Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Dec 1993 
 - 1112-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Oxidoreductases--antagonists & inhibitors<br/>Animals<br/>Aorta, Thoracic--drug effects<br/>Azoles--antagonists & inhibitors<br/>Benzamides--pharmacology<br/>Cattle<br/>Drug Interactions<br/>Endothelium, Vascular--drug effects<br/>Enzyme Activation<br/>Female<br/>Glutathione Peroxidase--metabolism<br/>In Vitro Techniques<br/>Isoindoles<br/>Male<br/>Muscle Relaxation--drug effects<br/>Muscle, Smooth, Vascular--drug effects<br/>Nitric Oxide Synthase<br/>Organoselenium Compounds--antagonists & inhibitors<br/>Rabbits<br/>Rats<br/>Rats, Wistar<br/>Sulfhydryl Compounds--pharmacology<br/>Swine