Heidelberger, C On the rational development of a new drug: the example of the fluorinated pyrimidines. [electronic resource] - Cancer treatment reports 1981 - 3-9 p. digital Publication Type: Journal Article ISSN: 0361-5960 Subjects--Topical Terms: AnimalsAntimetabolites, Antineoplastic--chemical synthesisBiotransformationDNA, Neoplasm--metabolismDeoxyuracil Nucleotides--metabolismFluorodeoxyuridylate--metabolismFluorouracil--analogs & derivativesHumansRNA, Neoplasm--metabolismThymidylate Synthase--antagonists & inhibitors