TY - GEN AU - Sigworth,F J AU - Spalding,B C TI - Chemical modification reduces the conductance of sodium channels in nerve SN - 0028-0836 PY - 1980///0324 KW - Animals KW - Anura KW - Cell Membrane Permeability KW - drug effects KW - Electric Conductivity KW - In Vitro Techniques KW - Ion Channels KW - Membrane Potentials KW - Onium Compounds KW - pharmacology KW - Rana pipiens KW - Ranvier's Nodes KW - Sodium KW - metabolism KW - Tetrodotoxin N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1038/283293a0 ER -