TY - GEN AU - Pettigrew,D W AU - Romeo,P H AU - Tsapis,A AU - Thillet,J AU - Smith,M L AU - Turner,B W AU - Ackers,G K TI - Probing the energetics of proteins through structural perturbation: sites of regulatory energy in human hemoglobin SN - 0027-8424 PY - 1982///0719 KW - Allosteric Regulation KW - Amino Acid Sequence KW - Chemical Phenomena KW - Chemistry, Physical KW - Hemoglobins KW - metabolism KW - Humans KW - Macromolecular Substances KW - Oxygen KW - Oxyhemoglobins KW - Protein Conformation KW - Structure-Activity Relationship KW - Thermodynamics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1073/pnas.79.6.1849 ER -