TY - GEN AU - Kanalas,J J AU - Suttle,D P TI - Amplification of the UMP synthase gene and enzyme overproduction in pyrazofurin-resistant rat hepatoma cells. Molecular cloning of a cDNA for UMP synthase SN - 0021-9258 PY - 1984///0316 KW - Amides KW - Animals KW - Antibiotics, Antineoplastic KW - toxicity KW - Base Sequence KW - Carboxy-Lyases KW - genetics KW - Cell Line KW - Cloning, Molecular KW - DNA KW - metabolism KW - Drug Resistance KW - Gene Amplification KW - Genes KW - Liver Neoplasms, Experimental KW - enzymology KW - Multienzyme Complexes KW - Orotate Phosphoribosyltransferase KW - Orotidine-5'-Phosphate Decarboxylase KW - Pentosyltransferases KW - Plasmids KW - Pyrazoles KW - RNA, Messenger KW - Rats KW - Ribonucleosides KW - Ribose N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S ER -