Omar, A M

Synthesis and evaluation of novel N-substituted N'-(3-hydroxy-17-oxoestra-1,3,5(10)-trien-2- and -4-yl)thiourea derivatives for binding to the estrogen receptor and cytotoxic activity on MCF-7 cells. [electronic resource] - Journal of pharmaceutical sciences Dec 1984 - 1871-3 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0022-3549

10.1002/jps.2600731263 doi


Animals
Antineoplastic Agents--chemical synthesis
Breast Neoplasms--pathology
Cell Division--drug effects
Cell Line
Chemical Phenomena
Chemistry
Estrenes--chemical synthesis
Estrogen Antagonists--chemical synthesis
Female
Humans
In Vitro Techniques
Rats
Receptors, Estrogen--metabolism
Thiourea--analogs & derivatives
Uterus--metabolism