Yamamoto, H <br/><br/>
Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets.  [electronic resource] 

 -  Biochemical and biophysical research communications  Jul 1980 
 - 474-81 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0006-291X 
<br/><br/><label>Standard No.: </label>10.1016/0006-291x(80)90762-7  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amides--pharmacology<br/>Animals<br/>Cell Nucleus--drug effects<br/>Diabetes Mellitus, Experimental--chemically induced<br/>Islets of Langerhans--drug effects<br/>Male<br/>NAD--metabolism<br/>NAD+ Nucleosidase--antagonists & inhibitors<br/>Niacinamide--pharmacology<br/>Picolinic Acids--pharmacology<br/>Poly(ADP-ribose) Polymerase Inhibitors<br/>Poly(ADP-ribose) Polymerases--metabolism<br/>Proinsulin--biosynthesis<br/>Rats<br/>Streptozocin--antagonists & inhibitors