Design and synthesis of naltrexone-derived affinity labels with nonequilibrium opioid agonist and antagonist activities. Evidence for the existence of different mu receptor subtypes in different tissues. [electronic resource]
- Journal of medicinal chemistry Oct 1984
- 1325-35 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
0022-2623
10.1021/jm00376a018 doi
Affinity Labels--chemical synthesis Animals Chemical Phenomena Chemistry Guinea Pigs Ileum--drug effects Indicators and Reagents Kinetics Magnetic Resonance Spectroscopy Male Mice Morphine--pharmacology Muscle, Smooth--drug effects Naloxone--analogs & derivatives Naltrexone--analogs & derivatives Receptors, Opioid--drug effects Receptors, Opioid, mu Structure-Activity Relationship Vas Deferens--drug effects