Rosowsky, A Synthesis and biological activity of tricyclic antifolate compounds with fixed geometry. [electronic resource] - Annals of the New York Academy of Sciences Nov 1971 - 258-69 p. digital Publication Type: Journal Article; Review ISSN: 0077-8923 Subjects--Topical Terms: Adenocarcinoma--drug therapyAnimalsAntineoplastic Agents--pharmacologyCarcinoma--drug therapyCell LineChickensEnterococcus faecalis--drug effectsFolic Acid Antagonists--chemical synthesisHumansLeukemia L1210--drug therapyLiver--enzymologyMalaria--drug therapyMammary Neoplasms, Experimental--drug therapyMiceMouth Neoplasms--drug therapyPyrimethamine--pharmacologyQuinazolines--therapeutic useStructure-Activity Relationship