TY - GEN AU - Teng-Leary,E AU - Kohlhaw,G B TI - Mechanism of feedback inhibition by leucine. Binding of leucine to wild-type and feedback-resistant alpha-isopropylmalate synthases and its structural consequences SN - 0006-2960 PY - 1973///1112 KW - Acetyl Coenzyme A KW - Binding Sites KW - Binding, Competitive KW - Caproates KW - Carbon Isotopes KW - Chromatography, Gel KW - Dialysis KW - Electrophoresis, Polyacrylamide Gel KW - Feedback KW - Hydrogen-Ion Concentration KW - Keto Acids KW - Kinetics KW - Leucine KW - Malates KW - Mutation KW - Oxo-Acid-Lyases KW - antagonists & inhibitors KW - Protein Binding KW - Protein Conformation KW - Salmonella typhimurium KW - enzymology KW - Spectrophotometry KW - Spectrophotometry, Ultraviolet KW - Valerates N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/bi00740a006 ER -