TY  - GEN
AU  - van Maanen,J M
AU  - de Ruiter,C
AU  - de Vries,J
AU  - Kootstra,P R
AU  - Gobas,F
AU  - Pinedo,H M
TI  - The role of metabolic activation by cytochrome P-450 in covalent binding of VP 16-213 to rat liver and HeLa cell microsomal proteins
SN  - 0277-5379
PY  - 1986///0116
KW  - Animals
KW  - Ascorbic Acid
KW  - pharmacology
KW  - Biotransformation
KW  - drug effects
KW  - Cytochrome P-450 Enzyme System
KW  - Etoposide
KW  - metabolism
KW  - HeLa Cells
KW  - Humans
KW  - In Vitro Techniques
KW  - Microsomes
KW  - Microsomes, Liver
KW  - NADP
KW  - Neoplasm Proteins
KW  - Nitrogen Oxides
KW  - Phenobarbital
KW  - Podophyllotoxin
KW  - analogs & derivatives
KW  - Proadifen
KW  - Protein Binding
KW  - Pyridines
KW  - Rats
KW  - Rats, Inbred Strains
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/0277-5379(85)90298-6
ER  -