Mathis, J M

Synergistic induction of monooxygenase activity by glucocorticoids and polycyclic aromatic hydrocarbons in human fetal hepatocytes in primary monolayer culture. [electronic resource] - Archives of biochemistry and biophysics Feb 1986 - 650-61 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0003-9861

10.1016/0003-9861(86)90633-8 doi


Aryl Hydrocarbon Hydroxylases--biosynthesis
Benz(a)Anthracenes--pharmacology
Benzo(a)pyrene--metabolism
Cells, Cultured
Coumarins--metabolism
Cytochrome P-450 Enzyme System--biosynthesis
Dexamethasone--pharmacology
Dose-Response Relationship, Drug
Drug Synergism
Enzyme Induction--drug effects
Female
Fetus--enzymology
Glucocorticoids--pharmacology
Humans
Hydrocortisone--analogs & derivatives
Hydroxylation
Kinetics
Liver--enzymology
Oxygenases--biosynthesis
Polycyclic Compounds--pharmacology
Pregnancy
Pregnenolone Carbonitrile--pharmacology
Receptors, Glucocorticoid--drug effects