Non-saturable degradation of LDL by monocyte-derived macrophages leads to a reduction in HMG-CoA reductase activity with little synthesis of cholesteryl esters. [electronic resource]
- Atherosclerosis Apr 1987
- 131-8 p. digital
Publication Type: Journal Article
0021-9150
10.1016/0021-9150(87)90238-3 doi
Cholesterol Esters--biosynthesis Humans Hydroxymethylglutaryl CoA Reductases--metabolism Hyperlipoproteinemia Type II--blood In Vitro Techniques Lipoproteins, LDL--metabolism Macrophages--enzymology Monocytes--enzymology Receptors, LDL--physiology