TY - GEN AU - Maurer,B J AU - Lai,E AU - Hamkalo,B A AU - Hood,L AU - Attardi,G TI - Novel submicroscopic extrachromosomal elements containing amplified genes in human cells SN - 0028-0836 PY - 1987///0630 KW - Drug Resistance KW - Extrachromosomal Inheritance KW - Gene Amplification KW - Genes KW - Genetic Variation KW - HeLa Cells KW - enzymology KW - Humans KW - Methotrexate KW - pharmacology KW - Tetrahydrofolate Dehydrogenase KW - genetics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1038/327434a0 ER -