TY  - GEN
AU  - Clarke,A R
AU  - Wigley,D B
AU  - Barstow,D A
AU  - Chia,W N
AU  - Atkinson,T
AU  - Holbrook,J J
TI  - A single amino acid substitution deregulates a bacterial lactate dehydrogenase and stabilizes its tetrameric structure
SN  - 0006-3002
PY  - 1987///0708
KW  - Allosteric Regulation
KW  - Allosteric Site
KW  - Arginine
KW  - Bacterial Proteins
KW  - genetics
KW  - Binding Sites
KW  - Fructosediphosphates
KW  - pharmacology
KW  - Geobacillus stearothermophilus
KW  - enzymology
KW  - Glutamine
KW  - L-Lactate Dehydrogenase
KW  - Mutation
KW  - NAD
KW  - metabolism
KW  - Protein Binding
KW  - Protein Conformation
KW  - drug effects
KW  - Pyruvates
KW  - Pyruvic Acid
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/0167-4838(87)90234-2
ER  -