Massive overproduction of dihydrofolate reductase in bacteria as a response to the use of trimethoprim. [electronic resource]
- European journal of biochemistry Feb 1987
- 473-6 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0014-2956
10.1111/j.1432-1033.1987.tb10664.x doi
Base Sequence Chromosomes, Bacterial Drug Resistance, Microbial--genetics Escherichia coli--drug effects Genes Promoter Regions, Genetic Tetrahydrofolate Dehydrogenase--biosynthesis Trimethoprim--pharmacology