TY - GEN AU - Struck,R F AU - Kirk,M C AU - Rice,L S AU - Suling,W J TI - Isolation, synthesis, and antitumor evaluation of spirohydantoin aziridine, a mutagenic metabolite of spirohydantoin mustard SN - 0022-2623 PY - 1987///0311 KW - Animals KW - Antineoplastic Agents KW - chemical synthesis KW - Aziridines KW - Azirines KW - Biotransformation KW - Drug Evaluation, Preclinical KW - Leukemia P388 KW - drug therapy KW - Mice KW - Microsomes, Liver KW - metabolism KW - Mutagenicity Tests KW - Mutagens KW - Mutation KW - Salmonella typhimurium KW - drug effects KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/jm00157a039 ER -