TY  - GEN
AU  - Rosowsky,A
AU  - Moran,R G
AU  - Freisheim,J H
AU  - Bader,H
AU  - Forsch,R A
AU  - Solan,V C
TI  - Synthesis and biologic activity of new side-chain-altered methotrexate and aminopterin analogs with dual inhibitory action against dihydrofolate reductase and folylpolyglutamate synthetase
SN  - 0893-2751
PY  - 1988///0304
KW  - Aminobutyrates
KW  - Aminopterin
KW  - analogs & derivatives
KW  - Animals
KW  - Cell Division
KW  - drug effects
KW  - Folic Acid Antagonists
KW  - chemical synthesis
KW  - Growth Inhibitors
KW  - Leukemia L1210
KW  - enzymology
KW  - Liver
KW  - Methotrexate
KW  - Mice
KW  - Ornithine
KW  - Peptide Synthases
KW  - antagonists & inhibitors
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
ER  -