Rosowsky, A <br/><br/>
Synthesis and biologic activity of new side-chain-altered methotrexate and aminopterin analogs with dual inhibitory action against dihydrofolate reductase and folylpolyglutamate synthetase.  [electronic resource] 

 -  NCI monographs : a publication of the National Cancer Institute  1987 
 - 145-52 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0893-2751 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminobutyrates<br/>Aminopterin--analogs & derivatives<br/>Animals<br/>Cell Division--drug effects<br/>Folic Acid Antagonists--chemical synthesis<br/>Growth Inhibitors<br/>Leukemia L1210--enzymology<br/>Liver--enzymology<br/>Methotrexate--analogs & derivatives<br/>Mice<br/>Ornithine--analogs & derivatives<br/>Peptide Synthases--antagonists & inhibitors<br/>Structure-Activity Relationship