Tiffen, Jessamy

EZH2 Cooperates with DNA Methylation to Downregulate Key Tumor Suppressors and IFN Gene Signatures in Melanoma. [electronic resource] - The Journal of investigative dermatology 12 2020 - 2442-2454.e5 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1523-1747

10.1016/j.jid.2020.02.042 doi


Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
Cell Line, Tumor
Chromatin Immunoprecipitation Sequencing
DNA Methylation--immunology
Datasets as Topic
Down-Regulation
Drug Resistance, Neoplasm--genetics
Enhancer of Zeste Homolog 2 Protein--antagonists & inhibitors
Female
Gene Expression Regulation, Neoplastic--immunology
Gene Silencing--immunology
Humans
Immune Checkpoint Inhibitors--pharmacology
Interferon-alpha--genetics
Interferon-gamma--genetics
Melanoma--drug therapy
Mice
Mutation
Neoplasm Invasiveness--genetics
RNA-Seq
Skin--immunology
Skin Neoplasms--drug therapy
Tumor Suppressor Proteins--genetics
Xenograft Model Antitumor Assays